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Leptin-mediated regulation of ICAM-1 is Rho/ROCK dependent and enhances gastric cancer cell migration

BACKGROUND: Our previous study indicates that leptin enhances gastric cancer (GC) invasion. However, the exact effect of leptin on GC metastasis and its underlying mechanism remain unclear. Intercellular adhesion molecule-1 (ICAM-1), a major molecule in stabilising cell–cell and cell–extracellular m...

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Detalles Bibliográficos
Autores principales: Dong, Z, Fu, S, Xu, X, Yang, Y, Du, L, Li, W, Kan, S, Li, Z, Zhang, X, Wang, L, Li, J, Liu, H, Qu, X, Wang, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974087/
https://www.ncbi.nlm.nih.gov/pubmed/24548863
http://dx.doi.org/10.1038/bjc.2014.70