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Nicotine increases the resistance of lung cancer cells to cisplatin through enhancing Bcl-2 stability
BACKGROUND: Nicotine is able to activate mitogenic signalling pathways, which promote cell growth or survival as well as increase chemoresistance of cancer cells. However, the underlying mechanisms are not fully understood. METHODS: In this study, we used immunoblotting and immunoprecipitation metho...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974091/ https://www.ncbi.nlm.nih.gov/pubmed/24548862 http://dx.doi.org/10.1038/bjc.2014.78 |