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Nicotine increases the resistance of lung cancer cells to cisplatin through enhancing Bcl-2 stability

BACKGROUND: Nicotine is able to activate mitogenic signalling pathways, which promote cell growth or survival as well as increase chemoresistance of cancer cells. However, the underlying mechanisms are not fully understood. METHODS: In this study, we used immunoblotting and immunoprecipitation metho...

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Detalles Bibliográficos
Autores principales: Nishioka, T, Luo, L-Y, Shen, L, He, H, Mariyannis, A, Dai, W, Chen, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974091/
https://www.ncbi.nlm.nih.gov/pubmed/24548862
http://dx.doi.org/10.1038/bjc.2014.78