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Tracking of time-varying genomic regulatory networks with a LASSO-Kalman smoother

It is widely accepted that cellular requirements and environmental conditions dictate the architecture of genetic regulatory networks. Nonetheless, the status quo in regulatory network modeling and analysis assumes an invariant network topology over time. In this paper, we refocus on a dynamic persp...

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Detalles Bibliográficos
Autores principales: Khan, Jehandad, Bouaynaya, Nidhal, Fathallah-Shaykh, Hassan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974129/
https://www.ncbi.nlm.nih.gov/pubmed/24517200
http://dx.doi.org/10.1186/1687-4153-2014-3