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Synergistic anti-inflammatory effect: simvastatin and pioglitazone reduce inflammatory markers of plasma and epicardial adipose tissue of coronary patients with metabolic syndrome

BACKGROUND: The inappropriate secretion of adipocytokines plays a critical role in chronic inflammatory states associated with obesity-linked type 2 diabetes and atherosclerosis. The pleiotropic actions of simvastatin and pioglitazone on epicardial adipose tissue (EAT) are unknown. This study assess...

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Detalles Bibliográficos
Autores principales: Grosso, Adriana Ferreira, de Oliveira, Sérgio Ferreira, Higuchi, Maria de Lourdes, Favarato, Desidério, Dallan, Luís Alberto de Oliveira, da Luz, Protásio Lemos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974153/
https://www.ncbi.nlm.nih.gov/pubmed/24684779
http://dx.doi.org/10.1186/1758-5996-6-47