Determining immune components necessary for progression of pigment dispersing disease to glaucoma in DBA/2J mice

BACKGROUND: The molecular mechanisms causing pigment dispersion syndrome (PDS) and the pathway(s) by which it progresses to pigmentary glaucoma are not known. Mutations in two melanosomal protein genes (Tyrp1( b ) and Gpnmb( R150X )) are responsible for pigment dispersing iris disease, which progres...

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Detalles Bibliográficos
Autores principales: Nair, K Saidas, Barbay, Jessica, Smith, Richard S, Masli, Sharmila, John, Simon WM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974199/
https://www.ncbi.nlm.nih.gov/pubmed/24678736
http://dx.doi.org/10.1186/1471-2156-15-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974199/
https://www.ncbi.nlm.nih.gov/pubmed/24678736
http://dx.doi.org/10.1186/1471-2156-15-42

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