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Determining immune components necessary for progression of pigment dispersing disease to glaucoma in DBA/2J mice
BACKGROUND: The molecular mechanisms causing pigment dispersion syndrome (PDS) and the pathway(s) by which it progresses to pigmentary glaucoma are not known. Mutations in two melanosomal protein genes (Tyrp1( b ) and Gpnmb( R150X )) are responsible for pigment dispersing iris disease, which progres...
Autores principales: | Nair, K Saidas, Barbay, Jessica, Smith, Richard S, Masli, Sharmila, John, Simon WM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974199/ https://www.ncbi.nlm.nih.gov/pubmed/24678736 http://dx.doi.org/10.1186/1471-2156-15-42 |
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