Pharmacophore and Virtual Screening of JAK3 inhibitors

Janus kinase 3 (JAK3) is a non-receptor tyrosine kinases family of protein which is comprised of JAK1, JAK2, JAK3 and TYK2. It plays an important role in immune function and lymphoid development and it only resides in the hematopoietic system. Therefore, selective targeting JAK3 is a rational approa...

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Detalles Bibliográficos
Autores principales: Rajeswari, Murugesan, Santhi, Natchimuthu, Bhuvaneswari, Vembu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2014
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974243/
https://www.ncbi.nlm.nih.gov/pubmed/24748756
http://dx.doi.org/10.6026/97320630010157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974243/
https://www.ncbi.nlm.nih.gov/pubmed/24748756
http://dx.doi.org/10.6026/97320630010157

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