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Association of HLA-DRB1-restricted CD4(+) T cell responses with HIV immune control

The contribution of HLA class II-restricted CD4(+) T cell responses to HIV immune control is poorly defined. Here, we delineated novel peptide-DRB1 restrictions in functional assays and analyzed the host genetic effects of HLA-DRB1 alleles on HIV viremia in a large cohort of HIV controllers and prog...

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Detalles Bibliográficos
Autores principales: Ranasinghe, Srinika, Cutler, Sam, Davis, Isaiah, Lu, Richard, Soghoian, Damien Z., Qi, Ying, Sidney, John, Kranias, Gregory, Flanders, Michael, Lindqvist, Madelene, Kuhl, Bjorn, Alter, Galit, Deeks, Steven G., Walker, Bruce D., Gao, Xiaojiang, Sette, Alessandro, Carrington, Mary, Streeck, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974408/
https://www.ncbi.nlm.nih.gov/pubmed/23793098
http://dx.doi.org/10.1038/nm.3229