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Association of HLA-DRB1-restricted CD4(+) T cell responses with HIV immune control
The contribution of HLA class II-restricted CD4(+) T cell responses to HIV immune control is poorly defined. Here, we delineated novel peptide-DRB1 restrictions in functional assays and analyzed the host genetic effects of HLA-DRB1 alleles on HIV viremia in a large cohort of HIV controllers and prog...
Autores principales: | Ranasinghe, Srinika, Cutler, Sam, Davis, Isaiah, Lu, Richard, Soghoian, Damien Z., Qi, Ying, Sidney, John, Kranias, Gregory, Flanders, Michael, Lindqvist, Madelene, Kuhl, Bjorn, Alter, Galit, Deeks, Steven G., Walker, Bruce D., Gao, Xiaojiang, Sette, Alessandro, Carrington, Mary, Streeck, Hendrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974408/ https://www.ncbi.nlm.nih.gov/pubmed/23793098 http://dx.doi.org/10.1038/nm.3229 |
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