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Protein Quantitative Trait Loci Identify Novel Candidates Modulating Cellular Response to Chemotherapy

Annotating and interpreting the results of genome-wide association studies (GWAS) remains challenging. Assigning function to genetic variants as expression quantitative trait loci is an expanding and useful approach, but focuses exclusively on mRNA rather than protein levels. Many variants remain wi...

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Detalles Bibliográficos
Autores principales: Stark, Amy L., Hause, Ronald J., Gorsic, Lidija K., Antao, Nirav N., Wong, Shan S., Chung, Sophie H., Gill, Daniel F., Im, Hae K., Myers, Jamie L., White, Kevin P., Jones, Richard Baker, Dolan, M. Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974641/
https://www.ncbi.nlm.nih.gov/pubmed/24699359
http://dx.doi.org/10.1371/journal.pgen.1004192