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Protein Quantitative Trait Loci Identify Novel Candidates Modulating Cellular Response to Chemotherapy
Annotating and interpreting the results of genome-wide association studies (GWAS) remains challenging. Assigning function to genetic variants as expression quantitative trait loci is an expanding and useful approach, but focuses exclusively on mRNA rather than protein levels. Many variants remain wi...
Autores principales: | Stark, Amy L., Hause, Ronald J., Gorsic, Lidija K., Antao, Nirav N., Wong, Shan S., Chung, Sophie H., Gill, Daniel F., Im, Hae K., Myers, Jamie L., White, Kevin P., Jones, Richard Baker, Dolan, M. Eileen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974641/ https://www.ncbi.nlm.nih.gov/pubmed/24699359 http://dx.doi.org/10.1371/journal.pgen.1004192 |
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