Cargando…

Exact Hybrid Particle/Population Simulation of Rule-Based Models of Biochemical Systems

Detailed modeling and simulation of biochemical systems is complicated by the problem of combinatorial complexity, an explosion in the number of species and reactions due to myriad protein-protein interactions and post-translational modifications. Rule-based modeling overcomes this problem by repres...

Descripción completa

Detalles Bibliográficos
Autores principales: Hogg, Justin S., Harris, Leonard A., Stover, Lori J., Nair, Niketh S., Faeder, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974646/
https://www.ncbi.nlm.nih.gov/pubmed/24699269
http://dx.doi.org/10.1371/journal.pcbi.1003544