Rax-CreER(T2) Knock-In Mice: A Tool for Selective and Conditional Gene Deletion in Progenitor Cells and Radial Glia of the Retina and Hypothalamus

To study gene function in neural progenitors and radial glia of the retina and hypothalamus, we developed a Rax-CreER(T2) mouse line in which a tamoxifen-inducible Cre recombinase is inserted into the endogenous Rax locus. By crossing Rax-CreER(T2) with the Cre-dependent Ai9 reporter line, we demons...

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Detalles Bibliográficos
Autores principales: Pak, Thomas, Yoo, Sooyeon, Miranda-Angulo, Ana M., Wang, Hong, Blackshaw, Seth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974648/
https://www.ncbi.nlm.nih.gov/pubmed/24699247
http://dx.doi.org/10.1371/journal.pone.0090381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974648/
https://www.ncbi.nlm.nih.gov/pubmed/24699247
http://dx.doi.org/10.1371/journal.pone.0090381

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