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Rax-CreER(T2) Knock-In Mice: A Tool for Selective and Conditional Gene Deletion in Progenitor Cells and Radial Glia of the Retina and Hypothalamus
To study gene function in neural progenitors and radial glia of the retina and hypothalamus, we developed a Rax-CreER(T2) mouse line in which a tamoxifen-inducible Cre recombinase is inserted into the endogenous Rax locus. By crossing Rax-CreER(T2) with the Cre-dependent Ai9 reporter line, we demons...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974648/ https://www.ncbi.nlm.nih.gov/pubmed/24699247 http://dx.doi.org/10.1371/journal.pone.0090381 |