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High-Throughput Screening for the Identification of New Therapeutic Options for Metastatic Pheochromocytoma and Paraganglioma

Drug repurposing or repositioning is an important part of drug discovery that has been growing in the last few years for the development of therapeutic options in oncology. We applied this paradigm in a screening of a library of about 3,800 compounds (including FDA-approved drugs and pharmacological...

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Detalles Bibliográficos
Autores principales: Giubellino, Alessio, Shankavaram, Uma, Bullova, Petra, Schovanek, Jan, Zhang, Yaqin, Shen, Min, Patel, Nikita, Elkahloun, Abdel, Lee, Min-Jung, Trepel, Jane, Ferrer, Marc, Pacak, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974653/
https://www.ncbi.nlm.nih.gov/pubmed/24699253
http://dx.doi.org/10.1371/journal.pone.0090458