Over-Expression of Either MECP2_e1 or MECP2_e2 in Neuronally Differentiated Cells Results in Different Patterns of Gene Expression

Mutations in MECP2 are responsible for the majority of Rett syndrome cases. MECP2 is a regulator of transcription, and has two isoforms, MECP2_e1 and MECP2_e2. There is accumulating evidence that MECP2_e1 is the etiologically relevant variant for Rett. In this study we aim to detect genes that are d...

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Detalles Bibliográficos
Autores principales: Orlic-Milacic, Marija, Kaufman, Liana, Mikhailov, Anna, Cheung, Aaron Y. L., Mahmood, Huda, Ellis, James, Gianakopoulos, Peter J., Minassian, Berge A., Vincent, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974668/
https://www.ncbi.nlm.nih.gov/pubmed/24699272
http://dx.doi.org/10.1371/journal.pone.0091742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974668/
https://www.ncbi.nlm.nih.gov/pubmed/24699272
http://dx.doi.org/10.1371/journal.pone.0091742

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