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Sensitization by Pulmonary Reactive Oxygen Species of Rat Vagal Lung C-Fibers: The Roles of the TRPV1, TRPA1, and P2X Receptors

Sensitization of vagal lung C-fibers (VLCFs) induced by mediators contributes to the pathogenesis of airway hypersensitivity, which is characterized by exaggerated sensory and reflex responses to stimulants. Reactive oxygen species (ROS) are mediators produced during airway inflammation. However, th...

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Detalles Bibliográficos
Autores principales: Ruan, Ting, Lin, Yu-Jung, Hsu, Tien-Huan, Lu, Shing-Hwa, Jow, Guey-Mei, Kou, Yu Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974698/
https://www.ncbi.nlm.nih.gov/pubmed/24699274
http://dx.doi.org/10.1371/journal.pone.0091763