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NhaA Na(+)/H(+) Antiporter Mutants That Hardly React to the Membrane Potential

pH and Na(+) homeostasis in all cells requires Na(+)/H(+) antiporters. The crystal structure, obtained at pH 4, of NhaA, the main antiporter of Escherichia coli, has provided general insights into an antiporter mechanism and its unique pH regulation. Here, we describe a general method to select vari...

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Detalles Bibliográficos
Autores principales: Alkoby, Dudu, Rimon, Abraham, Burdak, Maral, Patino-Ruiz, Miyer, Călinescu, Octavian, Fendler, Klaus, Padan, Etana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974702/
https://www.ncbi.nlm.nih.gov/pubmed/24699187
http://dx.doi.org/10.1371/journal.pone.0093200