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NhaA Na(+)/H(+) Antiporter Mutants That Hardly React to the Membrane Potential
pH and Na(+) homeostasis in all cells requires Na(+)/H(+) antiporters. The crystal structure, obtained at pH 4, of NhaA, the main antiporter of Escherichia coli, has provided general insights into an antiporter mechanism and its unique pH regulation. Here, we describe a general method to select vari...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974702/ https://www.ncbi.nlm.nih.gov/pubmed/24699187 http://dx.doi.org/10.1371/journal.pone.0093200 |