Gut Hormone Pharmacology of a Novel GPR119 Agonist (GSK1292263), Metformin, and Sitagliptin in Type 2 Diabetes Mellitus: Results from Two Randomized Studies

GPR119 receptor agonists improve glucose metabolism and alter gut hormone profiles in animal models and healthy subjects. We therefore investigated the pharmacology of GSK1292263 (GSK263), a selective GPR119 agonist, in two randomized, placebo-controlled studies that enrolled subjects with type 2 di...

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Detalles Bibliográficos
Autores principales: Nunez, Derek J., Bush, Mark A., Collins, David A., McMullen, Susan L., Gillmor, Dawn, Apseloff, Glen, Atiee, George, Corsino, Leonor, Morrow, Linda, Feldman, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974707/
https://www.ncbi.nlm.nih.gov/pubmed/24699248
http://dx.doi.org/10.1371/journal.pone.0092494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974707/
https://www.ncbi.nlm.nih.gov/pubmed/24699248
http://dx.doi.org/10.1371/journal.pone.0092494

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