Treatment of Erythrocytes with the 2-Cys Peroxiredoxin Inhibitor, Conoidin A, Prevents the Growth of Plasmodium falciparum and Enhances Parasite Sensitivity to Chloroquine

The human erythrocyte contains an abundance of the thiol-dependant peroxidase Peroxiredoxin-2 (Prx2), which protects the cell from the pro-oxidant environment it encounters during its 120 days of life in the blood stream. In malarial infections, the Plasmodium parasite invades red cells and imports...

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Detalles Bibliográficos
Autores principales: Brizuela, Mariana, Huang, Hong Ming, Smith, Clare, Burgio, Gaetan, Foote, Simon J., McMorran, Brendan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974718/
https://www.ncbi.nlm.nih.gov/pubmed/24699133
http://dx.doi.org/10.1371/journal.pone.0092411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974718/
https://www.ncbi.nlm.nih.gov/pubmed/24699133
http://dx.doi.org/10.1371/journal.pone.0092411

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