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Identification of Two Tyrosine Residues Required for the Intramolecular Mechanism Implicated in GIT1 Activation
GIT1 is an ArfGAP and scaffolding protein regulating cell adhesion and migration. The multidomain structure of GIT1 allows the interaction with several partners. Binding of GIT1 to some of its partners requires activation of the GIT1 polypeptide. Our previous studies indicated that binding of paxill...
Autores principales: | Totaro, Antonio, Astro, Veronica, Tonoli, Diletta, de Curtis, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974724/ https://www.ncbi.nlm.nih.gov/pubmed/24699139 http://dx.doi.org/10.1371/journal.pone.0093199 |
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