A Random Sequential Mechanism of Aminoglycoside Acetylation by Mycobacterium tuberculosis Eis Protein

An important cause of bacterial resistance to aminoglycoside antibiotics is the enzymatic acetylation of their amino groups by acetyltransferases, which abolishes their binding to and inhibition of the bacterial ribosome. Enhanced intracellular survival (Eis) protein from Mycobacterium tuberculosis...

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Detalles Bibliográficos
Autores principales: Tsodikov, Oleg V., Green, Keith D., Garneau-Tsodikova, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974725/
https://www.ncbi.nlm.nih.gov/pubmed/24699000
http://dx.doi.org/10.1371/journal.pone.0092370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974725/
https://www.ncbi.nlm.nih.gov/pubmed/24699000
http://dx.doi.org/10.1371/journal.pone.0092370

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