Comprehensive Logic Based Analyses of Toll-Like Receptor 4 Signal Transduction Pathway

Among the 13 TLRs in the vertebrate systems, only TLR4 utilizes both Myeloid differentiation factor 88 (MyD88) and Toll/Interleukin-1 receptor (TIR)-domain-containing adapter interferon-β-inducing Factor (TRIF) adaptors to transduce signals triggering host-protective immune responses. Earlier studie...

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Detalles Bibliográficos
Autores principales: Padwal, Mahesh Kumar, Sarma, Uddipan, Saha, Bhaskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974726/
https://www.ncbi.nlm.nih.gov/pubmed/24699232
http://dx.doi.org/10.1371/journal.pone.0092481