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Studies on Inhibition of Respiratory Cytochrome bc (1) Complex by the Fungicide Pyrimorph Suggest a Novel Inhibitory Mechanism
The respiratory chain cytochrome bc (1) complex (cyt bc (1)) is a major target of numerous antibiotics and fungicides. All cyt bc (1) inhibitors act on either the ubiquinol oxidation (Q(P)) or ubiquinone reduction (Q(N)) site. The primary cause of resistance to bc (1) inhibitors is target site mutat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974799/ https://www.ncbi.nlm.nih.gov/pubmed/24699450 http://dx.doi.org/10.1371/journal.pone.0093765 |