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Crosstalk between ERK, AKT, and cell survival

It is historically well known that signaling by the PI3K-AKT and MEK1/2-ERK1/2 pathways in a cell type-dependent fashion can collaborate to maintain cell viability.(1)(-)(3) Signaling pathways can also crosstalk with each other wherein one pathway can signal to either enhance or suppress signaling b...

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Detalles Bibliográficos
Autor principal: Dent, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974823/
https://www.ncbi.nlm.nih.gov/pubmed/24424114
http://dx.doi.org/10.4161/cbt.27541