The Pathogenic Mechanism of the Mycobacterium ulcerans Virulence Factor, Mycolactone, Depends on Blockade of Protein Translocation into the ER

Infection with Mycobacterium ulcerans is characterised by tissue necrosis and immunosuppression due to mycolactone, the necessary and sufficient virulence factor for Buruli ulcer disease pathology. Many of its effects are known to involve down-regulation of specific proteins implicated in important...

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Detalles Bibliográficos
Autores principales: Hall, Belinda S., Hill, Kirsti, McKenna, Michael, Ogbechi, Joy, High, Stephen, Willis, Anne E., Simmonds, Rachel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974873/
https://www.ncbi.nlm.nih.gov/pubmed/24699819
http://dx.doi.org/10.1371/journal.ppat.1004061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974873/
https://www.ncbi.nlm.nih.gov/pubmed/24699819
http://dx.doi.org/10.1371/journal.ppat.1004061

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