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A strategy for generation and balancing of autosome: Y chromosome translocations

We describe a method for generation and maintenance of translocations that move large autosomal segments onto the Y chromosome. Using this strategy we produced (2;Y) translocations that relocate between 1.5 and 4.8 Mb of the 2(nd) chromosome.. All translocations were easily balanced over a male-spec...

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Detalles Bibliográficos
Autores principales: Joshi, Sonal S, Cheong, Han, Meller, Victoria H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974896/
https://www.ncbi.nlm.nih.gov/pubmed/24646827
http://dx.doi.org/10.4161/fly.27814