H2A.B facilitates transcription elongation at methylated CpG loci

H2A.B is a unique histone H2A variant that only exists in mammals. Here we found that H2A.B is ubiquitously expressed in major organs. Genome-wide analysis of H2A.B in mouse ES cells shows that H2A.B is associated with methylated DNA in gene body regions. Moreover, H2A.B-enriched gene loci are activ...

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Detalles Bibliográficos
Autores principales: Chen, Yibin, Chen, Qiang, McEachin, Richard C., Cavalcoli, James D., Yu, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975057/
https://www.ncbi.nlm.nih.gov/pubmed/24402521
http://dx.doi.org/10.1101/gr.156877.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975057/
https://www.ncbi.nlm.nih.gov/pubmed/24402521
http://dx.doi.org/10.1101/gr.156877.113

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