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Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals

Long intergenic noncoding RNAs (lincRNAs) play diverse regulatory roles in human development and disease, but little is known about their evolutionary history and constraint. Here, we characterize human lincRNA expression patterns in nine tissues across six mammalian species and multiple individuals...

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Detalles Bibliográficos
Autores principales: Washietl, Stefan, Kellis, Manolis, Garber, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975061/
https://www.ncbi.nlm.nih.gov/pubmed/24429298
http://dx.doi.org/10.1101/gr.165035.113