Cargando…

High-throughput binding characterization of RNA aptamer selections using a microplate-based multiplex microcolumn device

We describe a versatile 96-well microplate-based device that utilizes affinity microcolumn chromatography to complement downstream plate-based processing in aptamer selections. This device is reconfigurable and is able to operate in serial and/or parallel mode with up to 96 microcolumns. We demonstr...

Descripción completa

Detalles Bibliográficos
Autores principales: Szeto, Kylan, Reinholt, Sarah J., Duarte, Fabiana M., Pagano, John M., Ozer, Abdullah, Yao, Li, Lis, John T., Craighead, Harold G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975076/
https://www.ncbi.nlm.nih.gov/pubmed/24553662
http://dx.doi.org/10.1007/s00216-014-7661-7