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High-throughput binding characterization of RNA aptamer selections using a microplate-based multiplex microcolumn device
We describe a versatile 96-well microplate-based device that utilizes affinity microcolumn chromatography to complement downstream plate-based processing in aptamer selections. This device is reconfigurable and is able to operate in serial and/or parallel mode with up to 96 microcolumns. We demonstr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975076/ https://www.ncbi.nlm.nih.gov/pubmed/24553662 http://dx.doi.org/10.1007/s00216-014-7661-7 |