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AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination
Secondary diversification of the antibody repertoire upon antigenic challenge, in the form of immunoglobulin heavy chain (IgH) class-switch recombination (CSR) endows mature, naïve B cells in peripheral lymphoid organs with a limitless ability to mount an optimal humoral immune response, thus expedi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975107/ https://www.ncbi.nlm.nih.gov/pubmed/24734031 http://dx.doi.org/10.3389/fimmu.2014.00120 |