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STRIDER: Sildenafil therapy in dismal prognosis early-onset intrauterine growth restriction – a protocol for a systematic review with individual participant data and aggregate data meta-analysis and trial sequential analysis

BACKGROUND: In pregnancies complicated by early-onset extreme fetal growth restriction, there is a high risk of preterm birth and an overall dismal fetal prognosis. Sildenafil has been suggested to improve this prognosis. The first aim of this review is to assess whether sildenafil benefits or harms...

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Detalles Bibliográficos
Autores principales: Ganzevoort, Wessel, Alfirevic, Zarko, von Dadelszen, Peter, Kenny, Louise, Papageorghiou, Aris, van Wassenaer-Leemhuis, Aleid, Gluud, Christian, Mol, Ben Willem, Baker, Philip N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975177/
https://www.ncbi.nlm.nih.gov/pubmed/24618418
http://dx.doi.org/10.1186/2046-4053-3-23