Cargando…

The number and genetic relatedness of transmitted/founder virus impact clinical outcome in vaginal R5 SHIV(SF162P3N) infection

BACKGROUND: Severe genetic bottleneck occurs during HIV-1 sexual transmission whereby most infections are initiated by a single transmitted/founder (T/F) virus. Similar observations had been made in nonhuman primates exposed mucosally to SIV/SHIV. We previously reported variable clinical outcome in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsai, Lily, Tasovski, Ivan, Leda, Ana Rachel, Chin, Mario PS, Cheng-Mayer, Cecilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975242/ https://www.ncbi.nlm.nih.gov/pubmed/24612462 http://dx.doi.org/10.1186/1742-4690-11-22

Ejemplares similares

Identification of interdependent variables that influence coreceptor switch in R5 SHIV(SF162P3N)-infected macaques
por: Zhuang, Ke, et al.
Publicado: (2012)

Gp120 V5 Is Targeted by the First Wave of Sequential Neutralizing Antibodies in SHIV(SF162P3N)-Infected Rhesus Macaques
por: Jia, Manxue, et al.
Publicado: (2018)

Mucosal transmissibility, disease induction and coreceptor switching of R5 SHIV(SF162P3N) molecular clones in rhesus macaques
por: Ren, Wuze, et al.
Publicado: (2013)

Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes
por: O’Brien, Sean P., et al.
Publicado: (2019)

HSV-2-Driven Increase in the Expression of α(4)β(7) Correlates with Increased Susceptibility to Vaginal SHIV(SF162P3) Infection
por: Goode, Diana, et al.
Publicado: (2014)

Transmitted/founder SHIV.D replicates in the brain, causes neuropathogenesis, and persists on combination antiretroviral therapy in rhesus macaques
por: Podgorski, Rachel M., et al.
Publicado: (2023)

Relatedness coefficients in pedigrees with inbred founders
por: Vigeland, Magnus Dehli
Publicado: (2020)

Rhesus macaques vaccinated with consensus envelopes elicit partially protective immune responses against SHIV SF162p4 challenge
por: Eugene, Hermancia S, et al.
Publicado: (2013)

Effect of MHC Haplotype on Immune Response upon Experimental SHIV(SF162P4cy) Infection of Mauritian Cynomolgus Macaques
por: Borsetti, Alessandra, et al.
Publicado: (2014)

SHIV-162P3 Infection of Rhesus Macaques Given Maraviroc Gel Vaginally Does Not Involve Resistant Viruses
por: Tsibris, Athe M. N., et al.
Publicado: (2011)

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques
por: Santra, Sampa, et al.
Publicado: (2015)

TLR7 Agonist GS–9620 Combined with Nicotinamide Generate Viral Reactivation in Seronegative SHIV(SF162P3)-Infected Rhesus Monkeys
por: Cong, Zhe, et al.
Publicado: (2023)

Sustained viremia suppression by SHIV(SF162P3CN)-recalled effector-memory CD8(+) T cells after PD1-based vaccination
por: Wong, Yik Chun, et al.
Publicado: (2021)

MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV(162P3) in Cynomolgus Macaques
por: Dereuddre-Bosquet, Nathalie, et al.
Publicado: (2012)

Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus
por: Lagenaur, Laurel A, et al.
Publicado: (2011)

A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α(4)β(7) and Fails to Prevent Mucosal Transmission of SHIV-SF162P3
por: Arrode-Brusés, Géraldine, et al.
Publicado: (2016)

Prevention of Vaginal SHIV Transmission in Macaques by a Coitally-Dependent Truvada Regimen
por: Radzio, Jessica, et al.
Publicado: (2012)

Correction: A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α(4)β(7) and Fails to Prevent Mucosal Transmission of SHIV-SF162P3
por: Arrode-Brusés, Géraldine, et al.
Publicado: (2016)

CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge
por: Ariën, Kevin K., et al.
Publicado: (2016)

Adapting SHIVs In Vivo Selects for Envelope-Mediated Interferon-α Resistance
por: Boyd, David F., et al.
Publicado: (2016)

Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction
por: Foster, Toshana L., et al.
Publicado: (2016)

P19-08. Immunisation with recombinant HLA class I and II, HIV-1gp140 and SIVp27 antigens elicits protection against SHIV-SF162P4 infection in rhesus macaques
por: Mörner, A, et al.
Publicado: (2009)

Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys.
por: Himes, Jonathon E., et al.
Publicado: (2018)

Broadly neutralizing antibodies potently inhibit cell-to-cell transmission of semen leukocyte-derived SHIV162P3
por: Suphaphiphat, Karunasinee, et al.
Publicado: (2020)

A MIV-150/Zinc Acetate Gel Inhibits SHIV-RT Infection in Macaque Vaginal Explants
por: Barnable, Patrick, et al.
Publicado: (2014)

An Antiretroviral/Zinc Combination Gel Provides 24 Hours of Complete Protection against Vaginal SHIV Infection in Macaques
por: Kenney, Jessica, et al.
Publicado: (2011)

Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques
por: Calenda, Giulia, et al.
Publicado: (2019)

A sequestered fusion peptide in the structure of an HIV-1 transmitted founder envelope trimer
por: Ananthaswamy, Neeti, et al.
Publicado: (2019)

Negative and Positive Selection Pressure During Sexual Transmission of Transmitted Founder HIV-1
por: Nijmeijer, Bernadien M., et al.
Publicado: (2019)

HIV-1 subtype C transmitted founders modulate dendritic cell inflammatory responses
por: Lumngwena, Evelyn Ngwa, et al.
Publicado: (2020)

Identification of early-induced broadly neutralizing activities against transmitted founder HIV strains
por: Lucas, Julie, et al.
Publicado: (2023)

Graphics for relatedness research
por: Galván‐Femenía, Iván, et al.
Publicado: (2017)

Sexually-Transmitted/Founder HIV-1 Cannot Be Directly Predicted from Plasma or PBMC-Derived Viral Quasispecies in the Transmitting Partner
por: Frange, Pierre, et al.
Publicado: (2013)

Mucosal application of the broadly neutralizing antibody 10-1074 protects macaques from cell-associated SHIV vaginal exposure
por: Suphaphiphat, Karunasinee, et al.
Publicado: (2023)

A deeper view of transmitted/founder viruses using 454 whole genome deep sequencing
por: Tully, DC, et al.
Publicado: (2012)

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome
por: Song, Hongshuo, et al.
Publicado: (2012)

Use of Dried Blood Spots to Elucidate Full-Length Transmitted/Founder HIV-1 Genomes
por: Salazar-Gonzalez, Jesus F., et al.
Publicado: (2016)

In vitro replicative fitness of early Transmitted founder HIV-1 variants and sensitivity to Interferon alpha
por: Ashok kumar, Manickam, et al.
Publicado: (2020)

Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction
por: Hertoghs, Nina, et al.
Publicado: (2019)

Generation and characterization of infectious molecular clones of transmitted/founder HIV-1 subtype C viruses
por: Luthuli, Bonisile, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_u737ped83s9ifmfs5co37dh6jf