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Neuroprotection by rAAV-mediated gene transfer of bone morphogenic protein 7

BACKGROUND: Bone morphogenic proteins (BMPs) promote the survival of neurons, suggesting a therapeutic application of BMPs in the treatment of acute and chronic neurodegenerative disorders. However, the application of recombinant BMPs in vivo is limited by their short half-life. To provide a continu...

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Detalles Bibliográficos
Autores principales: Heinonen, Ann-Marie, Rahman, Mahbubur, Dogbevia, Godwin, Jakobi, Hannah, Wölfl, Stefan, Sprengel, Rolf, Schwaninger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975265/
https://www.ncbi.nlm.nih.gov/pubmed/24618040
http://dx.doi.org/10.1186/1471-2202-15-38