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HBx Protein Promotes Oval Cell Proliferation by Up-Regulation of Cyclin D1 via Activation of the MEK/ERK and PI3K/Akt Pathways

Growing evidence has shown that hepatic oval cells, also named liver progenitor cells, play an important role in the process of liver regeneration in various liver diseases. Oval cell proliferation has been reported in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) and chronic liv...

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Detalles Bibliográficos
Autores principales: Wang, Heng-Yi, Yang, Sheng-Li, Liang, Hui-Fang, Li, Chang-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975350/
https://www.ncbi.nlm.nih.gov/pubmed/24577313
http://dx.doi.org/10.3390/ijms15033507