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Transport of Glial Cell Line-Derived Neurotrophic Factor into Liposomes across the Blood-Brain Barrier: In Vitro and in Vivo Studies

Glial cell line-derived neurotrophic factor (GDNF) was encapsulated into liposomes in order to protect it from enzyme degradation in vivo and promote its permeability across the blood-brain barrier (BBB). In this study, GDNF conventional liposomes (GDNF-L) and GDNF target sterically stabilized lipos...

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Detalles Bibliográficos
Autores principales: Wu, Shaoling, Li, Guoqi, Li, Xiao, Lin, Caina, Yu, Ding, Luan, Shuo, Ma, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975357/
https://www.ncbi.nlm.nih.gov/pubmed/24583850
http://dx.doi.org/10.3390/ijms15033612