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Perineural Dexmedetomidine Attenuates Inflammation in Rat Sciatic Nerve via the NF-κB Pathway

Recent studies have shown that dexmedetomidine exerts an anti-inflammatory effect by reducing serum levels of inflammatory factors, however, the up-stream mechanism is still unknown. The transcription factor NF-κB enters the nucleus and promotes the transcription of its target genes, including those...

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Detalles Bibliográficos
Autores principales: Huang, Yan, Lu, Yi, Zhang, Lei, Yan, Jia, Jiang, Jue, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975383/
https://www.ncbi.nlm.nih.gov/pubmed/24663080
http://dx.doi.org/10.3390/ijms15034049