Towards Controlling the Glycoform: A Model Framework Linking Extracellular Metabolites to Antibody Glycosylation

Glycoproteins represent the largest group of the growing number of biologically-derived medicines. The associated glycan structures and their distribution are known to have a large impact on pharmacokinetics. A modelling framework was developed to provide a link from the extracellular environment an...

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Detalles Bibliográficos
Autores principales: Jedrzejewski, Philip M., del Val, Ioscani Jimenez, Constantinou, Antony, Dell, Anne, Haslam, Stuart M., Polizzi, Karen M., Kontoravdi, Cleo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975410/
https://www.ncbi.nlm.nih.gov/pubmed/24637934
http://dx.doi.org/10.3390/ijms15034492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975410/
https://www.ncbi.nlm.nih.gov/pubmed/24637934
http://dx.doi.org/10.3390/ijms15034492

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