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Identification of the Novel Interacting Partners of the Mammalian Target of Rapamycin Complex 1 in Human CCRF-CEM and HEK293 Cells

The present study was undertaken to identify proteins that interact with the mammalian target of rapamycin complex 1 (mTORC1) to enable it to carry out its crucial cell signaling functions. Endogenous and myc-tag mTORC1 was purified, in-gel tryptic digested and then identified by nano-LC ESI Q-TOF M...

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Detalles Bibliográficos
Autores principales: Rahman, Hazir, Qasim, Muhammad, Oellerich, Michael, Asif, Abdul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975426/
https://www.ncbi.nlm.nih.gov/pubmed/24646917
http://dx.doi.org/10.3390/ijms15034823