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Targeting epidermal lipids for treatment of Mendelian disorders of cornification

BACKGROUND: Inherited ichthyoses or Mendelian disorders of cornification (MeDOC) are clinically heterogeneous disorders with high unmet therapeutic needs, which are characterized by skin hyperkeratosis and scaling. Some MeDOC types are associated with defects of the epidermal lipid metabolism, resul...

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Detalles Bibliográficos
Autores principales: Kiritsi, Dimitra, Schauer, Franziska, Wölfle, Ute, Valari, Manthoula, Bruckner-Tuderman, Leena, Has, Cristina, Happle, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975448/
https://www.ncbi.nlm.nih.gov/pubmed/24607067
http://dx.doi.org/10.1186/1750-1172-9-33