Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer

BACKGROUND: HIF-1α and CXCR4/CXCL12 have crucial roles in the metastatic process of colorectal cancer. Our aim was to study the significance of targeting HIF-1α and the CXCR4/CXCL12 axis in colorectal cancer to prevent the dissemination process in vitro. METHODS: We investigated CXCR4 and CXCR7 mRNA...

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Detalles Bibliográficos
Autores principales: Romain, Benoît, Hachet-Haas, Muriel, Rohr, Serge, Brigand, Cécile, Galzi, Jean-Luc, Gaub, Marie-Pierre, Pencreach, Erwan, Guenot, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975457/
https://www.ncbi.nlm.nih.gov/pubmed/24629239
http://dx.doi.org/10.1186/1476-4598-13-58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975457/
https://www.ncbi.nlm.nih.gov/pubmed/24629239
http://dx.doi.org/10.1186/1476-4598-13-58

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