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Parasitic antigens alter macrophage polarization during Schistosoma japonicum infection in mice

BACKGROUND: Schistosome eggs are trapped in host liver and elicit severe hepatic granulomatous inflammation, which can lead to periportal fibrosis, portal hypertension, hemorrhage, or even death in the host. It was reported that the macrophage plays an important role in host immune responses to schi...

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Detalles Bibliográficos
Autores principales: Zhu, Jifeng, Xu, Zhipeng, Chen, Xiaojun, Zhou, Sha, Zhang, Weiwei, Chi, Ying, Li, Wei, Song, Xian, Liu, Feng, Su, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975460/
https://www.ncbi.nlm.nih.gov/pubmed/24666892
http://dx.doi.org/10.1186/1756-3305-7-122