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Protective Effects of Diallyl Sulfide against Thioacetamide-Induced Toxicity: A Possible Role of Cytochrome P450 2E1

Effects of diallyl sulfide (DAS) on thioacetamide-induced hepatotoxicity and immunotoxicity were investigated. When male Sprague-Dawley rats were treated orally with 100, 200 and 400 mg/kg of DAS in corn oil for three consecutive days, the activity of cytochrome P450 (CYP) 2E1-selective p-nitropheno...

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Detalles Bibliográficos
Autores principales: Kim, Nam Hee, Lee, Sangkyu, Kang, Mi Jeong, Jeong, Hye Gwang, Kang, Wonku, Jeong, Tae Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975471/
https://www.ncbi.nlm.nih.gov/pubmed/24753821
http://dx.doi.org/10.4062/biomolther.2014.016