Cargando…

Protective Effects of Diallyl Sulfide against Thioacetamide-Induced Toxicity: A Possible Role of Cytochrome P450 2E1

Effects of diallyl sulfide (DAS) on thioacetamide-induced hepatotoxicity and immunotoxicity were investigated. When male Sprague-Dawley rats were treated orally with 100, 200 and 400 mg/kg of DAS in corn oil for three consecutive days, the activity of cytochrome P450 (CYP) 2E1-selective p-nitropheno...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Nam Hee, Lee, Sangkyu, Kang, Mi Jeong, Jeong, Hye Gwang, Kang, Wonku, Jeong, Tae Cheon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975471/ https://www.ncbi.nlm.nih.gov/pubmed/24753821 http://dx.doi.org/10.4062/biomolther.2014.016

Ejemplares similares

Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation
por: Shrestha, Riya, et al.
Publicado: (2018)

Investigation of the Regulatory Effects of Saccharin on Cytochrome P450s in Male ICR Mice
por: Jo, Jun Hyeon, et al.
Publicado: (2017)

Role of Intestinal Microbiota in Baicalin-Induced Drug Interaction and Its Pharmacokinetics
por: Noh, Keumhan, et al.
Publicado: (2016)

A Comparison of the In Vitro Inhibitory Effects of Thelephoric Acid and SKF-525A on Human Cytochrome P450 Activity
por: Song, Min, et al.
Publicado: (2014)

Pharmacokinetic Interaction of Chrysin with Caffeine in Rats
por: Noh, Keumhan, et al.
Publicado: (2016)

Protective Effects of Diallyl Sulfide and Curcumin Separately against Thallium-Induced Toxicity in Rats
por: Abdel-Daim, Mohamed M., et al.
Publicado: (2015)

Effects of Baicalin on Oral Pharmacokinetics of Caffeine in Rats
por: Noh, Keumhan, et al.
Publicado: (2015)

The Effects of Acute Hydrogen Sulfide Poisoning on Cytochrome P450 Isoforms Activity in Rats
por: Wang, Xianqin, et al.
Publicado: (2014)

Effects of Eupatilin and Jaceosidin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes
por: Ji, Hye Young, et al.
Publicado: (2010)

Fungal cytochrome P450 database
por: Park, Jongsun, et al.
Publicado: (2008)

Pharmacokinetics, toxicity, and cytochrome P450 modulatory activity of plumbagin
por: Sumsakul, Wiriyaporn, et al.
Publicado: (2016)

Effects of chronic cirrhosis induced by intraperitoneal thioacetamide injection on the protein content and Michaelis–Menten kinetics of cytochrome P450 enzymes in the rat liver microsomes
por: Chandrashekar, Devaraj Venkatapura, et al.
Publicado: (2022)

Inhibitory and Inductive Effects of Opuntia ficus indica Extract and Its Flavonoid Constituents on Cytochrome P450s and UDP-Glucuronosyltransferases
por: Jeong, Hyesoo, et al.
Publicado: (2018)

Metabolism and interactions of Ivermectin with human cytochrome P450 enzymes and drug transporters, possible adverse and toxic effects
por: Rendic, Slobodan P.
Publicado: (2021)

Dendropanoxide Alleviates Thioacetamide-induced Hepatic Fibrosis via Inhibition of ROS Production and Inflammation in BALB/(C) Mice
por: Kundu, Amit, et al.
Publicado: (2023)

Effects of cytochrome P450 oxidoreductase genotypes on the pharmacokinetics of amlodipine in healthy Korean subjects
por: Han, Ji Min, et al.
Publicado: (2020)

Role of cytochrome P450 genotype in the steps toward personalized drug therapy
por: Cavallari, Larisa H, et al.
Publicado: (2011)

Effect of Honokiol on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes
por: Jeong, Hyeon-Uk, et al.
Publicado: (2013)

A history of the roles of cytochrome P450 enzymes in the toxicity of drugs
por: Guengerich, F. Peter
Publicado: (2020)

Diallyl sulfide protects against dilated cardiomyopathy via inhibition of oxidative stress and apoptosis in mice
por: Pang, Shuo, et al.
Publicado: (2021)

Gastrodia elata rhizoma ameliorates thioacetamide-induced liver injury in dogs
por: Yoon, Hye-Bin, et al.
Publicado: (2023)

Effect of cytochrome P450 inhibition on toxicity of diclofenac in chickens: Unravelling toxicity in Gyps vultures
por: Locke, Sara, et al.
Publicado: (2022)

The Cytochrome P450 Homepage
por: Nelson, David R
Publicado: (2009)

Genetic polymorphism of cytochrome P450 as a biomarker of susceptibility to environmental toxicity.
por: Hong, J Y, et al.
Publicado: (1997)

Extrahepatic cytochrome P450s play an insignificant role in triptolide-induced toxicity
por: Wei, Yuan, et al.
Publicado: (2018)

Liver microsomal lipid enhances the activity and redox coupling of colocalized cytochrome P450 reductase‐cytochrome P450 3A4 in nanodiscs
por: Liu, Kang‐Cheng, et al.
Publicado: (2017)

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450
por: Campelo, Diana, et al.
Publicado: (2018)

Protective Effects of Nutria Bile against Thioacetamide-Induced Liver Injury in Mice
por: Kong, Joo-Yeon, et al.
Publicado: (2019)

Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors
por: Rahman, Mohammad A., et al.
Publicado: (2017)

Role of Glutathione Conjugation in 1-Bromobutane-induced Immunotoxicity in Mice
por: Lee, Sang Kyu, et al.
Publicado: (2010)

Altered remodeling of nucleolar machineries in cultured hepatocytes treated with thioacetamide.
por: Jeong, J. S., et al.
Publicado: (2001)

Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes
por: Kim, Ju-Hyun, et al.
Publicado: (2017)

Role of Metabolism by Intestinal Bacteria in Arbutin-Induced Suppression of Lymphoproliferative Response in vitro
por: Kang, Mi Jeong, et al.
Publicado: (2012)

Induction of apoptosis with diallyl disulfide in AGS gastric cancer cell line
por: Lee, Jeong-Eun, et al.
Publicado: (2011)

Hepatic Metabolism of Sakuranetin and Its Modulating Effects on Cytochrome P450s and UDP-Glucuronosyltransferases
por: Jeong, Hyesoo, et al.
Publicado: (2018)

Magma Seawater Inhibits Hepatic Lipid Accumulation through Suppression of Lipogenic Enzymes Regulated by SREBPs in Thioacetamide-Injected Rats
por: Woo, Minji, et al.
Publicado: (2019)

Cytochrome P450 2C19 enzyme, Cytochrome P450 2C9 enzyme, and Cytochrome P450 2D6 enzyme allelic variants and its possible effect on drug metabolism: A retrospective study
por: Naujokaitis, Domas, et al.
Publicado: (2021)

The FMN “140s Loop” of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450
por: Rwere, Freeborn, et al.
Publicado: (2021)

Amelioration of thioacetamide-induced liver toxicity in Wistar rats by rutin
por: Zargar, Seema, et al.
Publicado: (2017)

Protective effect of diallyl disulfide on cyclophosphamide-induced testicular toxicity in rats
por: Kim, Sung-Hwan, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_9o2mphplcss2es8fom88eooiik