12-O-Tetradecanoylphorbol-13-Acetate Induces Keratin 8 Phosphorylation and Reorganization via Expression of Transglutaminase-2

The stiffness of cancer cells is attributable to intermediate filaments such as keratin. Perinuclear reorganization via phosphorylation of specific serine residue in keratin is implicated in the deformability of metastatic cancer cells including the human pancreatic carcinoma cell line (PANC-1). 12-...

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Detalles Bibliográficos
Autores principales: Lee, Eun Ji, Park, Mi Kyung, Kim, Hyun Ji, Kang, June Hee, Kim, You Ri, Kang, Gyeoung Jin, Byun, Hyun Jung, Lee, Chang Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975474/
https://www.ncbi.nlm.nih.gov/pubmed/24753817
http://dx.doi.org/10.4062/biomolther.2014.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975474/
https://www.ncbi.nlm.nih.gov/pubmed/24753817
http://dx.doi.org/10.4062/biomolther.2014.007

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