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Vesicular Stomatitis Virus G Glycoprotein and ATRA Enhanced Bystander Killing of Chemoresistant Leukemic Cells by Herpes Simplex Virus Thymidine Kinase/Ganciclovir

Refractoriness of acute myeloid leukemia (AML) cells to chemotherapeutics represents a major clinical barrier. Suicide gene therapy for cancer has been attractive but with limited clinical efficacy. In this study, we investigated the potential application of herpes simplex virus thymidine kinase/gan...

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Detalles Bibliográficos
Autores principales: Hu, Chenxi, Chen, Zheng, Zhao, Wenjun, Wei, Lirong, Zheng, Yanwen, He, Chao, Zeng, Yan, Yin, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975477/
https://www.ncbi.nlm.nih.gov/pubmed/24753816
http://dx.doi.org/10.4062/biomolther.2013.112