Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to ΔPK oncolytic activity in melanoma

Oncolytic virotherapy is a promising strategy to reduce tumor burden through selective virus replication in rapidly proliferating cells. However, the lysis of slowly replicating cancer stem cells (CSC), which maintain neoplastic clonality, is relatively modest and the potential contribution of progr...

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Detalles Bibliográficos
Autores principales: Colunga, Aric, Bollino, Dominique, Schech, Amanda, Aurelian, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975656/
https://www.ncbi.nlm.nih.gov/pubmed/24553345
http://dx.doi.org/10.1038/gt.2014.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975656/
https://www.ncbi.nlm.nih.gov/pubmed/24553345
http://dx.doi.org/10.1038/gt.2014.6

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