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Gene transfer of arginine kinase to skeletal muscle using adeno-associated virus

In this study we tested the feasibility of non-invasively measuring phosphoarginine (PArg) after gene delivery of arginine kinase (AK) using an adeno-associated virus (AAV) to murine hindlimbs. This was achieved by evaluating the time course, regional distribution, and metabolic flux of PArg using (...

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Detalles Bibliográficos
Autores principales: Forbes, Sean C., Bish, Lawrence T., Ye, Fan, Spinazzola, Janelle, Baligand, Celine, Plant, Daniel, Vandenborne, Krista, Barton, Elisabeth R., Sweeney, H. Lee, Walter, Glenn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975678/
https://www.ncbi.nlm.nih.gov/pubmed/24572791
http://dx.doi.org/10.1038/gt.2014.9