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Gene transfer of arginine kinase to skeletal muscle using adeno-associated virus
In this study we tested the feasibility of non-invasively measuring phosphoarginine (PArg) after gene delivery of arginine kinase (AK) using an adeno-associated virus (AAV) to murine hindlimbs. This was achieved by evaluating the time course, regional distribution, and metabolic flux of PArg using (...
Autores principales: | Forbes, Sean C., Bish, Lawrence T., Ye, Fan, Spinazzola, Janelle, Baligand, Celine, Plant, Daniel, Vandenborne, Krista, Barton, Elisabeth R., Sweeney, H. Lee, Walter, Glenn A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975678/ https://www.ncbi.nlm.nih.gov/pubmed/24572791 http://dx.doi.org/10.1038/gt.2014.9 |
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