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Probabilistic approaches to alignment with tandem repeats

BACKGROUND: Short tandem repeats are ubiquitous in genomic sequences and due to their complex evolutionary history pose a challenge for sequence alignment tools. RESULTS: To better account for the presence of tandem repeats in pairwise sequence alignments, we propose a simple tractable pair hidden M...

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Detalles Bibliográficos
Autores principales: Nánási, Michal, Vinař, Tomáš, Brejová, Broňa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975930/
https://www.ncbi.nlm.nih.gov/pubmed/24580741
http://dx.doi.org/10.1186/1748-7188-9-3